GPU-based real-time 4D Patient Dose Reconstruction for Radiation Therapy Treatment Validation

Mu-Han Lin, Department of Radiation Oncology, University of Maryland School of Medicine
Matthias K. Gobbert, Department of Mathematics and Statistics, UMBC

Our objective is to develop a GPU-based real-time patient dose reconstruction framework and to produce an intuitive decision-support graphical user interface to be embedded in the clinical workflow. Prior to the treatment, patient’s anatomy geometry will be acquired using the in-room imaging technology and uploaded to a high performance GPU cluster. Both the patient/tumor motion and the beam delivery will be continuously tracked during the treatment and this information will be updated in real time for the 4D dose reconstruction. By the end of the treatment delivery, a decision would be made based on the difference between the reconstructed dose and the planned dose. The proposed work will ensure the safety and the quality of patients’ treatment.